Organosulfur Compounds
Medchemexpress LLC CB2R/FAAH modulator-3 | 2876918-67-9 | C22H31NO2 | 50 MG
CB2R/FAAH modulator-3 (compound 27) is a dual-targeting modulator that acts as a CB2R agonist and FAAH inhibitor, with Ki values of 20.1 nM for CB2R and 67.6 nM for CB1R, and an IC50 value of 3.4 μM for FAAH. At 10 μM, it reduces the production of pro-inflammatory cytokines TNFα, IFN-γ, IL-1β, and IL6 in unstimulated monocytes and macrophages. This modulator can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
- Molecular weight: 341.49
- Formula: C22H31NO2
- CAS no.: 2876918-67-9
- Appearance: Solid
- Color: White to off-white
- Purity: 99.71%
Medchemexpress LLC TDRL-551 10mM 1mL | 1644626-43-6 | 591.83 g·mol⁻1 | C25H23ClIN3O4 | 1 ML
Small-molecule replication protein A (RPA) inhibitor supplied as a 10 mM solution in DMSO (1 mL) for research use. Intended for in vitro studies of RPA-DNA interactions and combination effects with platinum-based chemotherapies.
- Supplied as 10 mM solution in DMSO, 1 mL.
- High purity (99.84%) suitable for biochemical assays.
- Chemical formula C25H23ClIN3O4, molecular weight 591.83 g·mol⁻1.
- Store frozen in solvent for stability (short- and long-term conditions apply).
- Also available in multiple solid sizes for experimental flexibility.
- For research use only; not for human or animal therapeutic use.
Medchemexpress LLC Cytochrome P450 1B1 antibody (YA1836) | 10 UL
Cytochrome P450 1B1 antibody (YA1836) is a rabbit-derived, non-conjugated IgG monoclonal antibody targeting Cytochrome P450 1B1. It is intended for research use only.
- Rabbit host
- Recombinant, monoclonal
- Species reactivity: Human, mouse, rat
- Immunogen: A synthesized peptide derived from human CYP1B1 aa400-543
- Isotype: IgG
- Appearance: Liquid
- Formulation: Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
- Storage & stability: Stored at -20°C for 1 year. Avoid repeated freeze/thaw cycles
- Shipping: Shipping with blue ice
- Applications & dilution ratios: WB (Western Blot): 1:500-1:1000, IHC-P (Immunohistochemistry-Paraffin): 1:50-1:100, FC (Flow Cytometry): 1:50-1:100
- Sensitivity: Endogenous
- Conjugation: Non-conjugated
- Modification: Unmodified
Medchemexpress LLC KAT modulator-1 | 1314006-43-3 | C20H36O2 | 50 MG
KAT modulator-1 is a laboratory chemical identified for research use only. It has a molecular formula of C20H36O2 and a molecular weight of 308.50. This substance appears as a solid and is considered stable under recommended storage conditions, though it has not been fully validated for medical applications.
- Not classified as a hazardous substance
- Stable under recommended storage conditions
- Store in a tightly sealed container in a cool, well-ventilated area
- Avoid direct sunlight and ignition sources
- Recommended powder storage: -20°C for 3 years, 4°C for 2 years
- Recommended in-solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC NR2F6 modulator-1 | 904449-84-9 | 99.5% | 419.45 | 100 MG
NR2F6 modulator-1 is a potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator. It can be used for researching immune modulation and modulation of cancer stem cell activity.
- Potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator.
- Useful for researching immune modulation.
- Useful for researching modulation of cancer stem cell activity.
Medchemexpress LLC 2H-Indol-2-one, 1,3-dihydro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1-(2-phenylethyl)- | 421578-93-0 | 99.8% | 371.43 g·mol⁻¹ | C24H21NO3 | 5 MG
GLP-1R modulator C5 is a small-molecule allosteric modulator that enhances GLP-1 binding to the GLP-1 receptor via a transmembrane site. It shows in vitro activity (EC50 1.59 ± 0.53 μM) and is provided for research applications with supporting characterization and handling data.
- Allosteric enhancement of GLP-1 binding (EC50 1.59 ± 0.53 μM).
- High reported purity of 99.81%.
- Molecular formula C24H21NO3; molecular weight 371.43 g·mol⁻¹.
- Soluble in DMSO at 50 mg/mL; ultrasonic assistance recommended.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months).
- Available in multiple small package sizes suitable for laboratory testing.
Medchemexpress LLC 2-Amino-5-methylpyrazine | 5521-58-4 | 99.7% | C5H7N3 | 1 G
2-Amino-5-methylpyrazine is an intermediate chemical compound primarily used in the synthesis of LPAR1 antagonists. This product is intended for research purposes only and not for patient use.
- Utilized as an intermediate for LPAR1 antagonist synthesis.
- Purity of 99.7%.
- Appears as a light brown to yellow solid.
- Highly soluble in DMSO.
- Store at 4°C, protected from light.
Apexbio Technology LLC Sulindac 38194-50-2 100mg
Sulindac (CAS 38194-50-2) is a nonsteroidal anti-inflammatory drug that functions as a prodrug and is metabolized in vivo to pharmacologically active sulindac sulfide and sulindac sulfone Sulindac sulfide acts as a cyclooxygenase inhibitor and modulates intracellular signaling pathways including the repression of ras activity Sulindac sulfone possesses antitumor properties independent of cyclooxygenase inhibition Due to these distinct metabolites and their activities sulindac is utilized in biomedical research for studying inflammatory processes cyclooxygenase-mediated pathways and the chemopreventive mechanisms involved in tumorigenesis
Medchemexpress LLC N-(4-Cyanophenyl)glycine | 42288-26-6 | 100.0% | C9H8N2O2 | 500 G
N-(4-Cyanophenyl)glycine is a Glycine derivative presented as a white to off-white solid, intended solely for research applications. This amino acid derivative is recognized for its commercial use as an ergogenic supplement. It influences the secretion of anabolic hormones, supports fuel supply during exercise, enhances mental performance during stress-related tasks, and aids in preventing exercise-induced muscle damage.
- Glycine derivative
- Used as an ergogenic supplement
- Influences secretion of anabolic hormones
- Supplies fuel during exercise
- Enhances mental performance during stress-related tasks
- Prevents exercise-induced muscle damage
- Solid, white to off-white appearance
- For research use only
Medchemexpress LLC 2-Amino-5-methylpyrazine | 5521-58-4 | 99.7% | C5H7N3 | 5 G
2-Amino-5-methylpyrazine is a chemical intermediate designed for research applications. It is utilized in the synthesis of LPAR1 antagonists. This product presents as a solid, ranging in color from light brown to yellow, and boasts a high purity of 99.72%.
- Functions as an intermediate for chemical synthesis.
- Enables the synthesis of LPAR1 antagonists.
- Exhibits a high purity.
- Available as a solid form.
- Displays a light brown to yellow coloration.
- Highly soluble in dimethyl sulfoxide.
- Features multiple dissolution protocols for in vivo studies.
- Intended exclusively for research purposes.
Medchemexpress LLC Cytochrome P450 24A1 Antibody (YA2121) | 50 UL
Cytochrome P450 24A1 Antibody (YA2121) is a rabbit-derived, non-conjugated IgG monoclonal antibody specifically targeting Cytochrome P450 24A1. This antibody is intended for research use only. Cytochrome P450 24A1 is a monooxygenase crucial for vitamin D catabolism and calcium homeostasis, inactivating calcidiol and calcitriol via C24- and C23-oxidation pathways.
- Host: Rabbit
- Clonality: Monoclonal
- Conjugation: Non-conjugated
- Isotype: IgG
- Appearance: Liquid
- Purity: Affinity chromatography
- Application: Western blot (WB)
- Dilution ratio: 1:500-1:1000
- Species reactivity: Human
- Molecular weight: 59 kDa (predicted and observed)
- Subcellular localization: Mitochondrion
- Research field: Cardiovascular